Are We as Old as Our NO

Background-—Impaired generation and signaling of nitric oxide (NO) contribute substantially to cardiovascular (CV) risk (CVR) associated with hypertension, hyperlipidemia, and diabetes mellitus. In our rapidly aging society, advanced age is, in itself, a consistent...

NO and Geriatrics

The nation’s aging population is growing rapidly. By 2030, the number of adults age 65 and older will nearly double to 70 million. Americans are living longer and older adults can now live for many years with multiple chronic illnesses but with a substantial cost to...

Aging and Pulse Wave Velocity in Relation to NO

The Pulse Wave Velocity (PWV) is an important marker of arterial stiffness. Age related changes of arterial stiffness in relation to PWV and endothelial derived Nitric Oxide (NOx) are least explored. Aim and Objectives: The present study was aimed to assess a...

Age Related Changes from Youth to Adult

Age related changes in brain cortex NO metabolism were investigated in mitochondria and cytosolic extracts from youth to adulthood. Decreases of 19%, 40% and 71% in NO production were observed in mitochondrial fractions from 3, 7, and 14 months old rats, respectively,...

NO Among Youth with Asthma

BACKGROUND: High fractional exhaled nitric oxide (FeNO) is an indicator of poor asthma control and has been proposed as a non-invasive assessment tool to guide asthma management. OBJECTIVE: We aimed to describe the prevalence of and factors associated with high FeNO...