by Skilling | Feb 19, 2023 | Memory |
Nitric oxide (NO) has been well established as a molecule necessary for memory consolidation. Interestingly, the majority of research has focused on only a single mechanism through which NO acts, namely the up-regulation of guanylate cyclase (GC). However, since NO...
by Skilling | Feb 19, 2023 | Memory |
The previously elusive and obscure chemical is proving to be of vital physiological significance. Nitric oxide may the firs tof a novel class of neurotransmitters. Read More
by Skilling | Feb 19, 2023 | Rest |
When mice are exposed to external warmth, nitric oxide synthase (NOS1) neurons in the median and medial preoptic (MnPO/MPO) hypothalamus induce sleep and concomitant body cooling. However, how these neurons regulate baseline sleep and body temperature is unknown....
by Skilling | Feb 19, 2023 | Rest |
This study was designed to investigate whether oxidative stress, nitric oxide (NO) deficiency and/or endothelial dysfunction (ED) are present in young borderline hypertensive rats (BHR) and whether these pathologies can be causally involved in the initiation of blood...
by Skilling | Feb 19, 2023 | Rest |
Stress is considered a risk factor associated with the development of various civilization diseases including cardiovascular diseases, malignant tumors and mental disorders. Research investigating mechanisms involved in stress-induced hypertension have attracted much...
by Skilling | Feb 19, 2023 | Rest |
The function of sleep remains one of the mysteries of the ages, yet sleep is an evolutionarily preserved behavior manifest in diverse organisms including worms (1), flies (2), and all vertebrates thus far examined (3). Perhaps one of the most compelling arguments for...
by Skilling | Feb 19, 2023 | Rest |
Nitric oxide inhibition abolishes sleep-wake differences in cerebral circulation. Am J Physiol Heart Circ Physiol 280: H2598–H2606, 2001.—Nitric oxide (NO), being produced by active neurones and also being a cerebral vasodilator, may couple brain activity and blood...
by Skilling | Feb 19, 2023 | Memory, Rest |
Basic and clinical studies demonstrate that depression is associated with reduced size of brain regions that regulate mood and cognition, including the prefrontal cortex and the hippocampus, and decreased neuronal synapses in these areas. Antidepressants can block or...
by Skilling | Feb 17, 2023 | Mobility |
We examined the role of nitric oxide (NO) in muscle repair and regeneration following repetitive eccentric contractions (ECC). A standardized exercise protocol was used to create eccentric contraction-induced injury to the left tibialis anterior muscle of 48 male...
by Skilling | Feb 17, 2023 | Mobility |
We investigated acute effects of NO synthase inhibition on exercise hemodynamics using NG-monomethyl-l-arginine (l-NMMA), a nonselective NO synthase -inhibitor. Healthy volunteers (n=10, 5 female, 19–33 years) participated in a 2-phase randomized crossover study,...
