NO in Inflammation and Pain Associated with OA

Osteoarthritis (OA) is a degenerative disease involving chondrocytes, cartilage and other joint tissues, and has a number of underlying causes, including both biochemical and mechanical factors. Although proinflammatory factors including nitric oxide (NO) are...

NO Role in Pathogenesis of RA and Lupus

Nitric oxide (NO) has been shown to regulate T cellfunctions under physiological conditions, but overproduction of NO may contribute to T lymphocyte dysfunction. NO-dependent tissue injury has been implicated in a variety of rheumatic diseases, including systemic...

NO for Treating Rheumatoid Arthritis

Di-tert-butyl dicarbonate, 4-nitro-O-phenylenediamine, guanidine hydrochloride, sodium sulfate, palladium on carbon (PD/C), tetrahydrofuran, Celite® 545 AW, acryloyl chloride, trimethylamine, TFA, pyrrolidine, acetonitrile, sodium methoxide, N,N’-dimethylformamide,...