Blog
UV Induced NO
Increasing evidence regarding positive effects of exposure to sunlight has led to suggestions that current advice may be overly weighted in favour of avoidance. UV-A has been reported to lower blood pressure, possibly through nitric oxide (NO) production in skin....
Visible Light-Controlled NO Release
Nitric oxide (NO) is a physiological signaling molecule, whose biological production is precisely regulated atthe subcellular level. Here, we describe the design, synthesis, and evaluation of novel mitochondria-targeted NO releasers, Rol-DNB-mor and Rol-DNB-pyr, that...
NO in color change
The ability of UV radiation to stimulate color change in vertebrates is well known; however, the signaling pathway involved is not fully explained. Since nitric oxide (NO) is among the candidates for this role, in this study the participation of NO signaling in the...
Suppression of Grasshopper Sound Production by NO-Releasing Neurons of the Central Complex
The central complex of acridid grasshoppers integrates sensory information pertinent to reproduction related acoustic communication. Activation of nitric oxide (NO)/cyclic GMP-signaling by injection of NO donors into the central complex of restrained Chorthippus...
Effect of Low-Frequency Therapeutic Ultrasound on Induction of NO in CKD
Introduction: Post-contrast acute kidney injury (PC-AKI) develops in a significant proportion of patients with CKD after invasive cardiology procedures and is strongly associated with adverse outcomes. Objective: We sought to determine whether increased internal...
Assessment of Nasal and Sinus NOOutput Using Single-Breath Humming Exhalations
Nasal nitric oxide (NO) levels increase greatly during humming compared to silent exhalation. In this study, the physiological and anatomical factors that regulate NO release during humming have been characterized in 10healthy subjects and in a model of the sinus and...
Light Induced NO Release in the Skin Beyond UVA
Nitric oxide (NO) is omnipresent in the body and synthesized by 3 isoenzymes (nNOS, eNOS and iNOS), all detected in human skin. NO can be stored in a pool of compounds readily converted to NO following skin irradiation by UVR and blue light. This non-enzymatic...
Blue Laser Light Increases Perfusion of a Skin Flap Via NO Release from Hemoglobin
Exposure to blue light decreases blood pressure, reducing the risk of developing cardiovascular disease, a new study from the University of Surrey and Heinrich Heine University Dusseldorf in collaboration with Philips reports. During this study, published in the...